Human glucose-6-phosphate dehydrogenase gene carried on a yeast artificial chromosome encodes active enzyme in monkey cells |
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| Authors: | M D'Urso I Zucchi A Ciccodicola G Palmieri F E Abidi D Schlessinger |
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| Affiliation: | International Institute of Genetics and Biophysics, Naples, Italy. |
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| Abstract: | Yeast artificial chromosomes (YACs) permit the cloning of large tracts of human DNA. A YAC containing the human glucose-6-phosphate dehydrogenase gene is shown to encode active enzyme, supporting the inference that the YAC conserves the structure of the genomic DNA. |
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