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Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120 |
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| Authors: | Esser M T Mori T Mondor I Sattentau Q J Dey B Berger E A Boyd M R Lifson J D |
| Affiliation: | Retroviral Pathogenesis Laboratory, AIDS Vaccine Program, SAIC-Frederick, Frederick, Maryland 21702, USA. |
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