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Dynamically repairing and replacing neural networks: using hybrid computational and biological tools
Authors:Sanchez Justin  Lytton William  Carmena Jose  Principe Jose  Fortes Jose  Barbour Randall  Francis Joseph
Institution:Department of Biomedical Engineering, Miami Project to Cure Paralysis, University of Miami, Coral Gables, Florida, USA. jcsanchez@ miami.edu
Abstract:The debilitating effects of injury to the nervous system can have a profound effect on daily life activities of the injured person. In this article, we present a project overview in which we are utilizing computational and biological principles, along with simulation and experimentation, to create a realistic computational model of natural and injured sensorimotor control systems. Through the development of hybrid in silico/biological coadaptive symbiotic systems, the goal is to create new technologies that yield transformative neuroprosthetic rehabilitative solutions and a new test bed for the development of integrative medical devices for the repair and enhancement of biological systems.
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