Antifungal activity of morinol B derivatives of tetrahydropyran sesquilignan |
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| Authors: | Masuda Kenta Nishiwaki Hisashi Akiyama Koichi Yamauchi Satoshi Maruyama Masafumi Sugahara Takuya Kishida Taro |
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| Institution: | Faculty of Agriculture, Ehime University, Matsuyama, Ehime, Japan. |
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| Abstract: | The relationship between the structure of naturally occurring (7R,7'R,8R,8'R)-morinol B and its antifungal activity was examined. 3-Demethoxy morinol B showed much higher activity than the natural compound. The activity of the 4-butoxy-3-demethoxy derivative was higher than that of 3-demethoxy morinol B. |
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