The principles of QTL analysis (a minimal mathematics approach) |
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Authors: | Kearsey M |
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Institution: | Plant Genetics Group, School of Biological Sciences, The University of Birmingham, Birmingham B15 2TT, UK |
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Abstract: | The combination of combination marker and trait data to explore the
individual genes concerned with quantitative traits, QTL analysis, has
become an important tool to allow biologists to dissect the genetics of
complex characters. However, the mathematical and statistical techniques
involved have deterred many from understanding what the methods achieved
and appreciating their strengths and weaknesses.This paper is designed to
give a non-mathematical explanation of the principles underlying these
analyses, to discuss their potential and to provide an introduction to the
techniques used in the subsequent papers in this series of articles based
on the SEB symposium.Key words: Gene mapping, QTL analysis, quantitative
genetics.
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