Potassium cyanate, an in vitro inhibitor of lymphocyte blast transformation without in vivo activity. |
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Authors: | A I Grayzel E F Roth C L Beck |
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Abstract: | Potassium cyanate (400 mug/ml) inhibited the blastogenesis of lymphocytes in response to PHA and the response of lymphocytes in mixed lymphocyte cultures. Cyanate administered to mice at a dose of 30 mg per kg per day did not delay allograft rejection. |
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