| 利用大孔树脂同时制备穿心莲内酯和脱水穿心莲内酯 |
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| 引用本文： | 吴娇,梅文莉,戴好富,彭明.利用大孔树脂同时制备穿心莲内酯和脱水穿心莲内酯[J].天然产物研究与开发,2009,21(6):1045-1048,1064. |
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| 作者姓名： | 吴娇 梅文莉 戴好富 彭明 |
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| 作者单位： | 1. 海南大学农学院,海口,570228;中国热带农业科学院热带生物技术研究所,农业部热带作物生物技术重点开放实验室,海口,571101
2. 中国热带农业科学院热带生物技术研究所,农业部热带作物生物技术重点开放实验室,海口,571101 |
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| 基金项目： | 中央级公益性科研院所基本科研业务费专项资金 |
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| 摘 要： | 采用大孔吸附树脂色谱法,以不同体积分数乙醇水溶液进行洗脱,分离富集穿心莲内酯和脱水穿心莲内酯,并配以HPLC进行同步监控.结果表明,穿心莲中这2种主要有效成分分别得到了富集.40%乙醇水溶液洗去目标物以外的杂质后,45%乙醇洗脱液中富含穿心莲内酯,含量为46.99%,55%乙醇洗脱液中富含脱水穿心莲内酯,含量为79.74%.
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| 关 键 词： | 穿心莲 穿心莲内酯 脱水穿心莲内酯 大孔树脂 |
Simultaneous Preparation of Andrographolide and Dehydroandrographolide Using Macroporous Resin |
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| WU Jiao,MEI Wen-li,DAI Hao-fu,PENG Ming.Simultaneous Preparation of Andrographolide and Dehydroandrographolide Using Macroporous Resin[J].Natural Product Research and Development,2009,21(6):1045-1048,1064. |
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| Authors: | WU Jiao MEI Wen-li DAI Hao-fu PENG Ming |
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| Abstract: | The optional elution conditions of macroporous adsorption resin for different diterpenoids in the ethanol extract of Andrographis paniculata were studied,and the process was monitored by HPLC.The result showed that two diterpenoids were enriched.After the impurities were abandoned in 40% ethanol aqueous solution,46.99% andrographolide was collected in 45% ethanol aqueous solution,and 14-deoxy-11,12-didehydroandrographolide was mainly enriched in 55% ethanol aqueous solution,in which the content of 14-deoxy-11,12-didehydroandrographolide was 79.74%. |
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| Keywords: | Andrographis paniculata Nees andrographolide dehydroandrographolide macroporous resin |
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