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Linkage analysis of 19 French breast cancer families, with five chromosome 17q markers.
Authors:S Mazoyer   P Lalle   S A Narod   Y J Bignon   F Courjal   B Jamot   B Dutrillaux   D Stoppa-Lyonnett     H Sobol
Abstract:Nineteen French breast and breast-ovarian cancer families were tested for linkage with five chromosome 17q markers. The five breast-ovarian cancer families as a group give positive evidence for linkage, whereas the 14 breast cancer-only families do not. Heterogeneity of linkage of breast and breast-ovarian cancers is significant in France and supports the existence of more than one susceptibility gene.
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