Linkage analysis of 19 French breast cancer families, with five chromosome 17q markers. |
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Authors: | S Mazoyer P Lalle S A Narod Y J Bignon F Courjal B Jamot B Dutrillaux D Stoppa-Lyonnett H Sobol |
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Abstract: | Nineteen French breast and breast-ovarian cancer families were tested for linkage with five chromosome 17q markers. The five breast-ovarian cancer families as a group give positive evidence for linkage, whereas the 14 breast cancer-only families do not. Heterogeneity of linkage of breast and breast-ovarian cancers is significant in France and supports the existence of more than one susceptibility gene. |
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