Potential of compact Compton sources in the medical field |
| |
| Institution: | 1. Department of Radiation Oncology, Mount Sinai Medical Center, New York, USA;2. Department of Computer Science, City College of New York, USA;3. Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, USA;1. Department of Physics, Stockholm University, Albanova University Center, SE-106 91 Stockholm, Sweden;2. Radiation Biophysics Group, Department of Oncology–Pathology, Karolinska Institutet, SE-17176 Stockholm, Sweden;1. Department of physics, SAS, VIT University, Vellore 632 014, Tamil Nadu, India;2. Department of medical physics, Apollo Gleneagles Hospital, Kolkata 700054, India;3. Centre for Nanotechnology Research, VIT University, Vellore 632 014, Tamil Nadu, India;1. Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania, Italy;2. School of Mathematics and Physics, Queens University Belfast, United Kingdom;3. Physics and Astronomy Department, University of Catania, Via S. Sofia 64, Catania, Italy;4. Institute of Physics ASCR, v.v.i (FZU), ELI-Beamlines Project, 182 21 Prague, Czech Republic;5. National Physical Laboratory, CMES – Medical Radiation Science Hampton Road, Teddington, Middlesex, TW11 0LW UK;1. Universidade Federal do Rio de Janeiro (UFRJ/COPPE/PEN), Ilha do Fundão, Caixa Postal 68590, Rio de Janeiro CEP, 21945-970 Rio de Janeiro, Brazil;2. Instituto de Radioproteção e Dosimetria/Comissão Nacional de Energia Nuclear (IRD/CNEN), Av. Salvador Allende, s/no, Barra da Tijuca, Rio de Janeiro CEP, 22783-127 Rio de Janeiro, Brazil;1. Department of Physics and Technology, University of Bergen, Postboks 7803, N-5020 Bergen, Norway;2. European Synchrotron Radiation Facility, 71 avenue des Martyrs, 38000 Grenoble, France;3. Centre for Medical Radiation Physics, University of Wollongong, NSW 2522, Australia;4. SINTEF MiNaLab, Department of Microsystems and Nanotechnology, Gaustadalléen 23 C, Oslo, Norway;5. Department of Physics, University of Oslo, Postboks 1048 Blindern, 0316 Oslo, Norway;6. Centre for Material Science and Nanotechnology, University of Oslo, Postboks 1048 Blindern, 0316 Oslo, Norway |
| |
| Abstract: | The exceptional improvement of high power lasers and optical cavity finesses in the last fifteen years allows today the development of X-ray sources based on inverse Compton scattering. These compact sources will provide high intensity beams, with a tunable energy in the range 20–100 keV, that can be used in several application including material sciences, structural biology, cultural heritage research and preservation and medical or biomedical preclinical and clinical research. The access to these devices will be easier. Methods currently used only in synchrotron facilities will be available in dedicated work environment such as hospitals, laboratories or museums. Several machines are in design or construction phase, and aim at producing 1012–1014 ph/s. The ThomX machine is the most advanced project and has the potential to be used as the radiation source for biomedical searches, clinical imaging techniques or radiotherapy programs. |
| |
| Keywords: | X-ray Compton source Medical field Imaging Therapy Adjuvant drugs |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
