Characterization of an α-Tubulin Gene of Cryptosporidium parvum |
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Authors: | MARÍA-TERESA BONAFONTE DEANNA GARMON JAN R MEAD |
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Institution: | VA Medical Center, Decatur, Georgia 30033, USA. |
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Abstract: | A gene encoding an alpha-tubulin of Cryptosporidium parvum was isolated and characterized. It had no introns, and encoded a 441-amino acid protein whose predicted ORF represented a typical alpha-tubulin protein with a MW of 50.5 kDa. This tubulin had an amino acid sequence similarity with Apicomplexa Plasmodium falciparum and Toxoplasma gondii higher than 88% and shared a number of conserved motifs. |
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Keywords: | Apicomplexa cytoskeleton Western blot |
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