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Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation
Authors:Christopher S. Smillie  Jenny Sauk  Dirk Gevers  Jonathan Friedman  Jaeyun Sung  Ilan Youngster  Elizabeth L. Hohmann  Christopher Staley  Alexander Khoruts  Michael J. Sadowsky  Jessica R. Allegretti  Mark B. Smith  Ramnik J. Xavier  Eric J. Alm
Affiliation:1. Broad Institute of MIT and Harvard, Cambridge, MA, USA;2. Computational and Systems Biology, MIT, Cambridge, MA, USA;3. The Center for Microbiome Informatics and Therapeutics, MIT, Cambridge, MA, USA;4. Division of Gastroenterology, Massachusetts General Hospital, Boston, MA, USA;5. Harvard Medical School, Boston, MA, USA;6. Department of Physics, MIT, Cambridge, MA, USA;7. Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA;8. Division of Infectious Diseases, Boston Children''s Hospital, Boston, MA, USA;9. Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA;10. BioTechnology Institute, University of Minnesota, St. Paul, MN, USA;11. Division of Gastroenterology, University of Minnesota, St. Paul, MN, USA;12. Center for Immunology, University of Minnesota, St. Paul, MA, USA;13. Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women''s Hospital, Boston, MA, USA;14. Finch Therapeutics, Somerville, MA, USA;15. Department of Biological Engineering, MIT, Cambridge, MA, USA
Abstract:
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  • Keywords:human microbiome  human microbiota  fecal transplant  fecal microbiota transplant  FMT  strain tracking  strain inference  bacterial engraftment
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