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A morphological and molecular study of Anaplasma phagocytophilum transmission events at the time of Ixodes ricinus tick bite
Authors:Erik G Granquist  Mona Aleksandersen  Karin Bergström  Stephen J Dumler  Wenche O Torsteinbø  Snorre Stuen
Affiliation:(1) Department of Production Animal Clinical Sciences, Section of Small Ruminant Research, Norwegian School of Veterinary Science, N-4325 Sandnes, Norway;(2) Department of Basic Sciences and Aquatic Medicine, Norwegian School of Veterinary Science, N-0033 Oslo, Norway;(3) National Veterinary Institute, 75189 Uppsala, Sweden;(4) Department of Pathology, Division of Medical Microbiology, The Johns Hopkins Hospital, 21205 Baltimore, MD, USA
Abstract:

Background  

Anaplasma phagocytophilum is the causative agent of human granulocytic anaplasmosis (HGA) in humans and tick-borne fever (TBF) in ruminants. The bacterium invades and replicates in phagocytes, especially in polymorphonuclear granulocytes.
Keywords:
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