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Mice expressing the variant rs1143679 allele of ITGAM (CD11b) show impaired DC-mediated T cell proliferation |
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| Authors: | Avery Justin T Jimenez Rachel V Blake Joseph L Wright Tyler T Le?n-Ruiz Beatriz Schoeb Trenton R Szalai Alexander J Bullard Daniel C |
| Institution: | 1.Department of Genetics, University of Alabama at Birmingham, 1700 University Blvd., Birmingham, AL, 35294-0013, USA ;2.Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA ;3.Department of Clinical and Health Sciences, University of Alabama at Birmingham, Birmingham, AL, USA ;4.Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA ; |
| Abstract: | Mammalian Genome - Genome-wide association studies (GWAS) and functional genomic analyses have implicated several ITGAM (CD11b) single-nucleotide polymorphisms (SNPs) in the development of SLE and... |
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