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Metabolic diversity within breast cancer brain-tropic cells determines metastatic fitness
Institution:1. Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA;2. Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA;3. Children’s Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA;4. Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA;5. Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA;6. Breast Cancer Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA;7. Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA;8. Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA
Abstract:
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  • Keywords:breast cancer brain metastasis  metastasis  metastatic latency  relapse  metabolism  late recurrences  immune surveillance  redox homeostasis  metastatic dormancy  HER2
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