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MiR-690 treatment causes decreased fibrosis and steatosis and restores specific Kupffer cell functions in NASH
Affiliation:1. Division of Endocrinology & Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA;2. Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA;3. Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA;4. Department of Surgery, University of California, San Diego, La Jolla, CA 92093, USA;5. Janssen Research & Development, Janssen Pharmaceutical Companies of Johnson & Johnson, Spring House, PA 19477, USA;6. Janssen Pharmaceutical Companies of Johnson & Johnson, San Francisco, CA 94080, USA
Abstract:
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  • Keywords:NASH  Kupffer cell  miR-690  fibrosis  steatosis  inflammation  liver
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