Ceramide metabolism in brain |
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| Authors: | Yasuo Kishimoto Nariko Kawamura |
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| Institution: | (1) John F. Kennedy Institute and Department of Neurology, John Hopkins University School of Medicine, 21205 Baltimore, Maryland, USA |
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| Abstract: | Summary Ceramide is the fundamental structure and key intermediate of all sphingolipids. Biosynthesis and catabolism of brain ceramide, especially their relationship to the metabolism of more complex sphingolipids in brain, are reviewed. Human genetic diseases which involve altered ceramide metabolism are also discussed. |
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