1. Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA;2. Department of Human Genetics and Graduate Program in Genetics and Molecular Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
Abstract:
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Highlights? MBD1 governs the proliferation and differentiation of neural stem cells (NSCs) ? MBD1 controls the expression of miRNAs, including miR-184, in NSCs ? MiR-184 represses the expression of Numblike ? Numblike rescues the effects of abnormal MBD1 and miR-184 expression