Antibacterial constituents from Leucosceptrum canum |
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| Authors: | Krishna Prasad Devkota Bruno Ndjakou Lenta Jean Duplex Wansi Norbert Sewald |
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| Institution: | 1. Department of Chemistry, Organic and Bioorganic Chemistry, Bielefeld University, P.O. Box 100131, 33501 Bielefeld, Germany;2. Institute of Forestry, Pokhara Campus, Tribhuvan University, P.O. Box 43, Pokhara, Kaski, Nepal;3. Department of Chemistry, Higher Teachers Training College, University of Yaoundé I, P.O. Box 47, Yaoundé, Cameroon |
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| Abstract: | Four new long-chain compounds, leucoperoxyterpene (1), leucoester (2), leucoic acid (3), and leucoenoic acid (4) has been isolated from aerial parts of the medicinal plant Leucosceptrum canum together with fifteen known compounds. Compound 1 was found to be a member of the rare class of peroxy open chain natural products. The structures of all compounds were assigned by means of modern spectroscopic techniques. All compounds were tested for their antibacterial activities against Bacillus subtilis, Escherichia coli, Micrococcus luteus, Pseudomonas agarici, Streptococcus minor, and Streptococcus ferus, in which, compounds 1, and 10–15 exhibited potent to moderate activities. |
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