Secondary metabolites from Calotropis procera (Aiton) |
| |
| Authors: | Kamel H. Shaker Nagy Morsy Heidi Zinecker Johannes F. Imhoff Bernd Schneider |
| |
| Affiliation: | 1. Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knöll-Str. 8, 07745 Jena, Germany;2. National Research Centre, Chemistry of Natural Compounds, El-bohouth St., Dokki, Cairo, Egypt;3. Kieler Wirkstoff-Zentrum, IFM-GEOMAR, Am Kiel-Kanal 44, 24106 Kiel, Germany |
| |
| Abstract: | Three new metabolites, 5-hydroxy-3,7-dimethoxyflavone-4′-O-β-glucopyranoside (1), 2β,19-epoxy-3β,14β-dihydroxy-19-methoxy-5α-card-20(22)-enolide (4) and β-anhydroepidigitoxigenin-3β-O-glucopyranoside (5), along with two known compounds, uzarigenine (2) and β-anhydroepidigitoxigenin (3), were isolated from Calotropis procera (Asclepiadaceae). The structure elucidation was accomplished mainly by nuclear magnetic resonance (NMR) spectroscopic and mass spectrometric methods. To examine putative antimicrobial or cytotoxic activities, various bioassays were performed. Uzarigenine (2) demonstrated moderate cytotoxicity. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
