Phenolic constituents of Gnaphalium uliginosum L. |
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| Authors: | Alexander N Shikov Maria Kundracikova Tony L Palama Olga N Pozharitskaya Vera M Kosman Valery G Makarov Bertalan Galambosi Hye Jin Kim Young Pyo Jang Young Hae Choi Robert Verpoorte |
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| Institution: | 1. Saint-Petersburg Institute of Pharmacy, 47/33 Piskarevskiy pr., 195067 St.-Petersburg, Russia;2. Interregional Center “Adaptogen”, 47/5 Piskarevskiy pr., 195067 St.-Petersburg, Russia;3. Division of Pharmacognosy, Section Metabolomics, Institute of Biology, Leiden University, P.O. Box 9502, 2333 CC Leiden, The Netherlands;4. UMR C53 - Peuplements Végétaux et Bioagresseurs en Milieu Tropical, Faculté des Sciences et Technologies, Université de La Réunion, 15 avenue René Cassin, B.P. 7151, 97715 Saint Denis Messag. Cedex 9, La Réunion, France;5. MTT Agrifood Research Finland, Plant Production Research, Karilantie 2 A, FI-50600 Mikkeli, Finland;7. College of Pharmacy, Kyung Hee University, Seoul 130-701, Republic of Korea |
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| Abstract: | The herb Gnaphalium uliginosum L. is an annual plant widely used in Russian and Bulgarian phytotherapy in the treatment of hypertension, thrombophlebitis, phlebothrombosis and ulcers. Decoction and infusion of G. uliginosum are known to possess anti-inflammatory, astringent, and antiseptic properties. Oil extracts are used in the treatment of laryngitis, upper respiratory catarrh and tonsillitis. However, there is still lack of information about the active compounds.Ten phenolic compounds have been identified from the aerial parts of G. uliginosum including seven flavonoid glucosides and three phenylpropanoids. Their chemical structures were elucidated on the basis of 1D and 2D NMR and HRESIMS. Among the identified compounds the first full assignments of the 1H and 13C NMR spectra of, 5,7,4′-trihydroxy-6,3′-dimethoxyflavone-7-O-β-d-(6″-O-caffeoyl)-glucopyranoside are firstly reported in this paper. |
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