Chiral separation of thiazide diuretics by HPLC on Chiralcel OD-RH,Chiralcel OJ-R and Chirobiotic-T phases |
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| Authors: | Visegrády Balázs Konecsni Tünde Grobuschek Nina Schmid Martin G Kilár Ferenc Aboul-Enein Hassan Y Gübitz Gerald |
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| Institution: | Central Research Laboratory, Faculty of Medicine, University of Pécs, Szigeti út 12, H-7643 Pécs, Hungary. |
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| Abstract: | This contribution deals with comparative studies on the chiral separation of thiazide diuretics using cellulose tris(3,5-dimethylphenylcarbamate) (Chiralcel OD-RH), cellulose tris(4-methylbenzoate) (Chiralcel OJ-R) and teicoplanin (Chirobiotic T) phases. All columns showed good chiral recognition ability for this class of compounds. Out of seven compounds investigated, six were resolved with baseline resolution with at least one of the three columns. |
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