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Effects of mobile phone radiofrequency on the structure and function of the normal human hemoglobin
Authors:Seyed Jafar Mousavy  Gholam Hossein Riazi  Mahmood Kamarei  Hadi Aliakbarian  Naghmeh Sattarahmady  Ahmad Sharifizadeh  Shahrokh Safarian  Faizan Ahmad  Ali Akbar Moosavi–Movahedi
Affiliation:1. Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran;2. Faculty of Electrical and Computer Engineering, University of Tehran, Tehran, Iran;3. School of Biology, College of Science, University of Tehran, Tehran, Iran;4. Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, India;5. Foundation for Advancement of Science and Technology in Iran (FAST-IR), Tehran, Iran;6. Department of Biochemistry, Shiraz University of Medical Sciences, Shiraz, Iran
Abstract:Widespread use of mobile phones has increased the human exposure to electromagnetic fields (EMFs). It is required to investigate the effect of EMFs on the biological systems. In this paper the effect of mobile phone RF (910 MHz and 940 MHz) on structure and function of HbA was investigated. Oxygen affinity was measured by sodium dithionite with UV–vis spectrophotometer. Structural changes were studied by circular dichroism and fluorescence spectroscopy. The results indicated that mobile phone EMFs altered oxygen affinity and tertiary structure of HbA. Furthermore, the decrease of oxygen affinity of HbA corresponded to the EMFs intensity and time of exposure.
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