Peroxisome proliferator-activated receptor gamma: its role in metabolic syndrome |
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Authors: | Pakala Rajbabu Kuchulakanti Pramod Rha Seung-Woon Cheneau Edouard Baffour Richard Waksman Ron |
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Institution: | Cardiovascular Research Institute, Washington Hospital Center, 110 Irving Street NW, Suite 4B-1, Washington, DC 20010, USA. |
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Abstract: | Here we review PPARgamma function in relation to human adipogenesis, insulin sensitization, lipid metabolism, blood pressure regulation and prothrombotic state to perhaps provide justification for this nuclear receptor remaining a key therapeutic target for the continuing development of agents to treat human metabolic syndrome. |
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