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In vivo efficacy of Ingavirin against pandemic A (H1N1/09)v influenza virus |
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| Authors: | Shishkina L N Nebol'sin V E Skarnovich M O Kabanov A S Sergeev A A Erdyneeva U B Serova O A Demina O K Agafonov A P Stavski? E A Drozdov I G |
| Abstract: | Ingavirin was shown to be efficient in inhibition of the pandemic influenza virus strains A/California/04/2009 (H1N1)v, A/California/07/2009 (H1N1)v, A/Moscow/225/2009 (H1N1)v and A/Moscow/226/2009 (H1N1)v. as well as the influenza virus strain A/Aichi/2/68 (H3N2) in the lungs of the infected mice. After oral administration of Ingavirin the titers of the influenza virus strains in the lung homogenates lowered. |
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