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2-(Aminomethyl)-benzamide-based glycine transporter type-2 inhibitors |
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| Authors: | Ho Koc-Kan Appell Kenneth C Baldwin John J Bohnstedt Adolph C Dong Guizhen Guo Tao Horlick Robert Islam Khondaker R Kultgen Steven G Masterson Christopher M McDonald Edward McMillan Kirk Morphy J Richard Rankovic Zoran Sundaram Hardy Webb Maria |
| Institution: | Pharmacopeia, Inc., PO Box 5350, Princeton, NJ 08543-5350, USA. kanho@pharmacorp.com |
| Abstract: | Structure-activity studies on benzamide 1 obtained from library screening led to the discovery of a novel series of potent and selective glycine transporter type-2 inhibitors. |
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