Thyroid hormones in chronic heat exposed men |
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| Authors: | A. Gertner R. Israeli A. Lev Y. Cassuto |
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| Affiliation: | (1) Present address: Division of Environmental Physiology, The Johns Hopkins University, 615 North Wolfe Street, 21205 Baltimore, Maryland, USA;(2) Departments of Biology and Occupational Health, The Ben Gurion University of the Negev, P.O. Box 653, 84120 Beer Sheva, Israel |
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| Abstract: | Previous reports have indicated that thyroid gland activity, is depressed in the heat. Total thyroxine (T4) and triiodothyronine (T3) serum levels in 17 workers of the metal work shop at a plant near the Dead Sea and 8 workers in Beer Sheva, Israel were examined. The metal workshop of the plant near the Dead Sea is part of a large chemical plant. The one in Beer Sheva is part of a large construction company. Maintenance work, as well as metal work projects are performed in both workshops. During the work shifts, the workers of the Dead Sea plant were exposed to temperatures ranging from 30–36°C (May–Oct.) and 14–21°C (Dec.–Feb). In Beer Sheva the range was 25–32°C (June–Sept.) and 10– 17°C (Dec.–Feb.). Total T4 was measured by competitive protein binding and total T3 by radioimmunoassay in blood drawn before work (0700) in July and January. In summer. T4 was higher and T3 was lower for both groups than in winter. The observed summer T3 decrease may result from depressed extrathyroidal conversion of T4 to T3. We conclude that the regulation of energy metabolism in hot climates may be related to extrathyroidal conversion of T4 to T3.This study was part of A. Gertner's Ph.D. Research Dissertation |
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