Age- and Gender-Based Studies of Trace Metal Levels and Various Enzymes Associated with Myocardial Infarction |
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Authors: | Farhana Mazhar Saadia R Tariq Farooq Bashir |
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Institution: | (1) Central Research Lab., Lahore College for Women University, Lahore, Pakistan; |
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Abstract: | The present investigation deals with the determination of various serum enzymes known to be elevated during myocardial infarction
(MI) and estimation of selected metals like Cu, Cr, Co, Fe, Pb, and Mg by flame atomic absorption spectrophotometry. The data
obtained thereby were processed for the determination of correlation coefficient matrix among the cardiac enzymes and the
serum metals. The study evidenced the accumulation of Pb during MI and reduction in the level of Fe. A significant negative
correlation was observed between Cu and creatine kinase-MB. The data were also segregated into various groups to study the
influence of age and gender on the levels of selected parameters. In both the genders, the age of the patients was found to
be correlated significantly with various cardiac enzymes. In case of male patients, the most significant correlation was observed
between age and blood sugar at random. The other significant correlations among the male patients included Cr–CPK, Cr–creatine
kinase-MB, Fe–age, and others. In female patients, the pairs of studied parameters that exhibited significant correlations
included age–lactic dehydrogenase, creatine phosphokinase isoenzyme–aspartate aminotransferase, lactic dehydrogenase–creatine
phosphokinase isoenzymes, Pb-Fe, and Cu-Co in addition to others. |
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Keywords: | |
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