Human chromosomal heteromorphisms in american blacks |
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Authors: | Ram S Verma Harvey Dosik |
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Institution: | (1) Division of Hematology and Cytogenetics, The Jewish Hospital and Medical Center of Brooklyn, 11238 Brooklyn, NY, USA;(2) Department of Medicine, State University of New York, Downstate Medical Center, 11238 Brooklyn, NY, USA;(3) Division of Cytogenetics, The Jewish Hospital and Med. Ctr., 555 Prospect Place, 11238 Brooklyn, NY, USA |
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Abstract: | Summary One hundred normal American Blacks (B) were studied by sequential QFQ and RFA banding techniques in order to estimate the type and frequency of heteromorphisms. Color heteromorphisms were classified into one of six colors by RFA and intensity variation into one of five levels by QFQ. The data are compared with a previously studied Caucasian population (C). The frequencies of QFQ and RFA heteromorphisms were significantly higher in the Black than in the Caucasian population. No racial difference was noted for chromosome 21 by QFQ, while RFA demonstrated a clear difference. It is concluded that the maximum characterization of racial differences of human chromosomal heteromorphisms was far greater by RFA than with QFQ. The present study suggests differences in QFQ and RFA heteromorphisms among the two races. |
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