Two new triterpenoid saponins from Gymnema sylvestre |
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Authors: | Zhu Xu-Min Xie Ping Di Ying-Tong Peng Shu-Lin Ding Li-Sheng Wang Ming-Kui |
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Affiliation: | ( Chengdu Institute of Biology, the Chinese Academy of Sciences;, Chengdu 610041, China;The West China College of Stomatology, Sichuan University;, Chengdu 610041, China) |
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Abstract: | Two new oleanane-type triterpenoid saponins, gymnemoside-W1 and W2, together with seven known compounds were isolated from the leaves of Gymnema sylvestre R. Br. By means of spectral and chemical analysis, the structures of the new compounds were elucidated as 16 β-hydroxyl olean-12-en-3-O-[β-D-glucopyranosyl (1→6)-β.D-glucopyranosyl]-28-O-β-D-glucopyranoside(1) and 16 β,21 β,28-trihydroxyl-olean-12-ene-3-O-glucoronopyranoside (2). The EtOHIH2O extracts of this plant were shown to be able to inhibit glucose absorption in rats. |
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Keywords: | Gymnema sylvestre gymnemoside-W1 and W2 triterpenoid Saponin. |
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