Synthesis and Application of C2 and C3 Symmetric (R)‐Phenylglycinol‐Derived Chiral Stationary Phases |
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| Authors: | Jeongjae Yu Dong Hyun Ryoo Jung Mi Lee Jae Jeong Ryoo |
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| Institution: | 1. Department of Chemistry, Kyungpook National University, Daegu, Korea;2. Department of Chemistry Education, Kyungpook National University, Daegu, Korea |
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| Abstract: | A C3 symmetric (R)‐phenylglycinol N‐1,3,5‐benzenetricarboxylic acid‐derived chiral stationary phase (CSP) and three C2 symmetric (R)‐phenylglycinol CSPs were newly synthesized using o‐, m‐, and p‐phthaloyl dichlorides. © 2016 Wiley Periodicals, Inc. These CSPs were used to compare the resolution of 25 chiral samples using a previously reported 3,5‐dinitrobenzoyl (R)‐phenylglycinol‐derived CSP. Even though all CSPs have the same chiral moiety, the C3 symmetric CSP showed the best resolution. Chirality 28:186–191, 2016.© 2016 Wiley Periodicals, Inc. |
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| Keywords: | 1 3 5‐benzenetricarboxylic acid C2 symmetry C3 symmetry (R)‐phenylglycinol CSP chiral HPLC |
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