Specific T-cell response to a Pneumocystis carinii surface glycoprotein (gp120). |
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| Authors: | D J Fisher F Gigliotti M Zauderer A G Harmsen |
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| Institution: | Department of Pediatrics, University of Rochester, School of Medicine and Dentistry, NY 14642. |
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| Abstract: | Pneumocystis carinii gp120 can elicit a specific T-cell proliferative response in mice after immunization with a gp120 preparation or with a crude P. carinii homogenate. It can also elicit a proliferative response from SCID mice after recovery from natural infection with P. carinii, implicating this glycoprotein as an important antigen in the host's response to P. carinii infection. |
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