Stereospecificity of ethanol oxidation |
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| Authors: | H Gang A I Cederbaum E Rubin |
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| Affiliation: | 1. Department of Pathology Mount Sinai School of Medicine of the City University of New York, N.Y. 10029 USA;2. Department of Biochemistry Mount Sinai School of Medicine of the City University of New York, N.Y. 10029 USA;3. Department of Laboratories Hospital for Joint Diseases and Medical Center, New York, N.Y. 10035 USA |
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| Abstract: | The stereospecificity of ethanol oxidation via alcohol dehydrogenase, the microsomal ethanol oxidizing system (MEOS) and catalase was determined using stereospecific ethanol-1-3H. All systems showed the same stereospecificity towards ethanol. All pathways displayed an isotope effect, but the effect with MEOS and catalase was greater than with alcohol dehydrogenase. |
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