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Geldanamycin-Induced Morphological Changes Require Candida albicans Hyphal Growth Regulatory Machinery
Authors:Saville  Stephen P.  Cleary  Ian A.
Affiliation:1.Department of Biology, The South Texas Center for Emerging Infectious Diseases, The University of Texas At San Antonio, San Antonio, TX, USA
;2.Department of Biomedical Sciences, Grand Valley State University, One Campus Drive, Allendale, MI, 49401, USA
;
Abstract:Mycopathologia - In Candida albicans, geldanamycin treatment inhibits the essential chaperone Hsp90 and induces a change from yeast to filamentous morphology, likely by impeding cell cycle...
Keywords:
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