Meiotic alterations in CAG repeat tracts. |
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Authors: | J K Schweitzer S S Reinke D M Livingston |
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Institution: | Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, USA. |
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Abstract: | We have investigated meiotic changes in CAG repeat tracts embedded in a yeast chromosome. Repeat tracts undergo either conversion events between homologs or expansion and contraction events that appear to be confined to a single chromatid. We did not find evidence for conversion of tract interruptions or excess exchange of flanking markers. |
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