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The Protein Data Bank and lessons in data management
Authors:Bourne Philip E  Westbrook John  Berman Helen M
Institution:Professor of Pharmacology at UCSD, Director of Integrative Biosciences at SDSC, and a Co-Director of the PDB. His research interests focus on structural bioinformatics and high performance computing as applied to problems in genomics and proteomics.
Abstract:The Protein Data Bank (PDB) is a widely used biological databaseof macromolecular structures with a long history. This historyis treated as lessons learned and is used to highlight whatare believed to be the best practices important to developersof biological databases today. While the focus is on data quality,data representation and the information technology to supportthese data, the non-data and technology issues cannot be ignored.The role of the human factor in the form of users, collaborators,scientific society and ad hoc committees is also included.
Keywords:PDB  mmCIF  macromolecular structure data  the human factor  data uniformity
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