| Biomarkers for Primary Sjgren's Syndrome |
| |
| 摘 要： | Primary Sjo¨gren's syndrome(p SS) is a systemic autoimmune disease with exocrine gland dysfunction and multi-organ involvement. Recent progress in understanding the pathogenesis of p SS offers an opportunity to find new biomarkers for the diagnosis and assessment of disease activity. Screening noninvasive biomarkers from the saliva and tears has significant potential. The need for specific and sensitive biomarker candidates in p SS is significant. This review aims to summarize recent advances in the identification of biomarkers of Sjo¨gren syndrome, trying to identify reliable, sensitive, and specific biomarkers that can be used to guide treatment decisions.
|
| 收稿时间： | 2015 Mar 10 |
Biomarkers for Primary Sj?gren’s Syndrome |
| |
| Authors: | Weiqian Chen Heng Cao Jin Lin Nancy Olsen Song Guo Zheng |
| |
| Institution: | 1.Division of Rheumatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China;2.Division of Rheumatology, Penn State University Hershey College of Medicine, Hershey, PA 17033, USA |
| |
| Abstract: | Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease with exocrine gland dysfunction and multi-organ involvement. Recent progress in understanding the pathogenesis of pSS offers an opportunity to find new biomarkers for the diagnosis and assessment of disease activity. Screening noninvasive biomarkers from the saliva and tears has significant potential. The need for specific and sensitive biomarker candidates in pSS is significant. This review aims to summarize recent advances in the identification of biomarkers of Sjögren syndrome, trying to identify reliable, sensitive, and specific biomarkers that can be used to guide treatment decisions. |
| |
| Keywords: | Biomarker Fms-like tyrosine kinase 3 ligand Myxovirus-resistance protein A Non-coding RNAs Saliva Sjögren syndrome |
| 本文献已被 CNKI 等数据库收录！ |
|
