Apport de la scintigraphie parathyroïdienne au 99mTc-MIBI en double phase dans l’exploration des hyperparathyroïdies. À propos de 20 cas |
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| Authors: | I Ghfir N Ben Raïs |
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| Institution: | 1. Institut de recherche en cancérologie de Montpellier (IRCM), Inserm U896, avenue des Apothicaires, 34298 Montpellier cedex 05, France;2. Avenue des Apothicaires, 34298 Montpellier cedex 05, France;3. Université Montpellier 1, avenue des Apothicaires, 34298 Montpellier cedex 05, France;4. Pôle de radiothérapie oncologique, ICM, institut régional du cancer Montpellier, rue Croix-Verte, 34298 Montpellier cedex 05, France;5. Laboratoire de biostatistique, d’épidémiologie et de recherche clinique, IURC, EA 2415, université Montpellier 1, avenue du Doyen-Giraud, 34093 Montpellier, France;6. Service de radio-oncologie, CHU Vaudois, rue du Bugnon 46, 1011 Lausanne, Suisse;7. Département de radiothérapie, CRLC Val d’Aurelle-Paul-Lamarque, rue Croix-Verte, 34298 Montpellier cedex 5, France;1. Service de médecine nucléaire, hôpital Huriez, CHU de Lille, rue Michel-Polonovski, 59000 Lille, France;2. Université Lille Nord de France, Lille, France;3. Service de chirurgie digestive et transplantation, CHU de Lille, rue Michel-Polonovski, 59000 Lille, France;1. Service de médecine nucléaire, hôpital Haut-Lévêque, CHU de Bordeaux, université de Bordeaux, avenue de Magellan, 33604 Pessac, France;2. Service de médecine nucléaire, CHU La Timone, CERIMED, université Aix-Marseille, 264, rue Saint-Pierre, 13385 Marseille, France;1. Service de biophysique et médecine nucléaire, UFR sciences médicales (SMA), université de Cocody, 28 BP 230, Abidjan 28, Côte d’Ivoire;2. Service de médecine nucléaire, CHU Jean-Minjoz, boulevard A.-Fleming, 25030 Besançon, France |
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| Abstract: | Introduction99mTc-sestamibi parathyroid scintigraphy is a means of functional imaging allowing the exploration of hyperparathyroidism. The aim of our study is to demonstrate the utility of double-phase 99mTc-sestamibi scintigraphy in the exploration of the secreting abnormal parathyroid gland.Materials and methodsWe report, through this work, the observation of 20 patients followed for a biologically ascertained hyperparathyroidism and explored, for the majority of them, by ultrasonography and/or computed tomography. All our patients benefited from a double-phase 99mTc-sestamibi scintigraphy.ResultsOn the 20 studied cases, the sex-ratio was equal to 1, two patients exhibited three high uptake foci at the 99mTc-sestamibi scintigraphy, six exhibited two foci, twelve exhibited one parathyroid focus. In our series, 80% of patients exhibited secondary hyperparathyroidism and 20% exhibited a primary hyperparathyroidism. The pathologic exam revealed four cases of parathyroid adenoma and 16 parathyroid cases of hyperplasia.DiscussionThe double-phase 99mTc-sestamibi scintigraphy contributes to the orientation and the improvement of the surgical attitude of the hyperparathyroidism, insofar as it could affirm the multiplicity of some adenomas, the diffuse form of some hyperplasias, and especially ectopic localization of the abnormal parathyroid gland. |
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