Inhibition of dihydropteridine reductase by dopamine |
| |
Authors: | Sheila E Purdy John A Blair and Patricia A Barford |
| |
Institution: | Department of Chemistry, University of Aston in Birmingham, Gosta Green, Birmingham B4 7ET, U.K. |
| |
Abstract: | Dihydropteridine reductase has been purified 900-fold from rat liver. Dopamine inhibited the enzyme up to 50% at a concentration of 0.11mm. In the presence of dopamine the enzyme gave non-hyperbolic v-against-S] plots. This enzyme may have a role in control of dopamine biosynthesis. |
| |
Keywords: | |
|
|