Intrinsically photosensitive retinal ganglion cells |
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Authors: | Gary E. Pickard Patricia J. Sollars |
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Affiliation: | Gary E.PICKARD & Patricia J.SOLLARS School of Veterinary Medicine , Biomedical Sciences,University of Nebraska,Lincoln NE 68583,USA |
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Abstract: | A new mammalian photoreceptor was recently discovered to reside in the ganglion cell layer of the inner retina.These intrinsically photosensitive retinal ganglion cells(ipRGCs) express a photopigment,melanopsin,that confers upon them the ability to respond to light in the absence of all rod and cone photoreceptor input.Although relatively few in number,ipRGCs extend their dendrites across large expanses of the retina making them ideally suited to function as irradiance detectors to assess changes in ambient... |
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Keywords: | melanopsin circadian rhythms suprachiasmatic nucleus retina pupillary light reflex |
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