Anisaldehyde, a melanogenesis potentiator |
| |
Authors: | Nitoda Teruhiko Fan Maria D Kubo Isao |
| |
Affiliation: | Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720, USA. |
| |
Abstract: | Anisaldehyde (4-methoxybenzaldehyde), previously reported as a tyrosinase inhibitor, did not inhibit melanogenesis in cultured B16-F10 melanoma cells but rather enhanced it. This adverse effect of anisaldehyde was accompanied by melanocytotoxicity in a dose-dependent manner up to 2 mM. The melanin content per cell at 1 mM was increased 5-fold compared to control and morphological observations showed the deposition of melanin pigments. Anisaldehyde was also examined against cultured human A375 melanoma cells. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|