The prognostic value of baseline erosions in undifferentiated arthritis |
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Authors: | Mohamed M Thabet Thomas WJ Huizinga Désirée M van der Heijde Annette HM van der Helm-van Mil |
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Affiliation: | (1) Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, PO Box 9600, 2300RC Leiden, The Netherlands;(2) Department of Internal Medicine, Assiut University Hospital, University Street 1, P.O. Box 71515, Assiut, Egypt |
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Abstract: | Introduction Undifferentiated arthritis (UA) has a variable disease course; 40 to 50% of UA patients remit spontaneously, while 30% develop rheumatoid arthritis (RA). Identifying the UA patients who will develop RA is essential to initiate early disease-modifying anti-rheumatic drug (DMARD) therapy. Although the presence of bone erosions at baseline is predictive for a severe destructive disease course in RA, the prognostic importance of erosive joints for disease outcome in UA is unknown. This study evaluates the predictive value of erosive joints for the disease outcome in UA as measured by RA development and disease persistency. |
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