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A factor from endothelium facilitates activation of plasminogen by tissue plasminogen activator |
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| Authors: | R Machovich W G Owen |
| Institution: | Section of Hematology Research, Mayo Clinic/Foundation, Rochester, Minn. |
| Abstract: | A component extracted from endothelium and partially purified has been found to have a capacity to enhance the rate of plasminogen activation by tissue-type plasminogen activator. The mechanism of action of this cofactor differs from that of others, such as fibrin. |
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