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Steroidal saponins from the rhizomes of Paris delavayi
Authors:Ting Zhang  Hai Liu  Xue-Ting Liu  Xiao-Qing Chen  Qiang Wang
Affiliation:1. Murad Research Center for Modernized Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;2. Department of Chinese Materia Medica Analysis, China Pharmaceutical University, Nanjing 210009, China;3. Shanghai Mass Spectrometry Center, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, Shanghai 200032, China;4. Department of Chemistry, University of Wisconsin-La Crosse, La Crosse, WI 54601, USA
Abstract:Two new steroidal saponins, padelaosides A (1) and B (2), along with two other known steroidal saponins (3 and 4) were isolated from the rhizomes of Paris delavayi. Their structures were elucidated by 1D and 2D NMR techniques, HRFTMS, physical data and chemical methods. The two different absolute configurations of fucose, assigned as l and d that were found on compounds 1 and 2, respectively, were simultaneously reported in a natural medicine for the first time.
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