Steroid regulation of sexual behavior. |
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| Authors: | C Beyer G Morali K Larsson P S?derstein |
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| Affiliation: | 1. Department of Psychology, University of Toronto, 100 St. George Street, Toronto, ON M5S 3G3, Canada;2. Department of Neuroscience, University of Toronto, 100 St. George Street, Toronto, ON M5S 3G3, Canada;3. Department of Cells and Systems Biology, University of Toronto, 100 St. George Street, Toronto, ON M5S 3G3, Canada;1. Evolutionary Anthropology Research Group, Behaviour Ecology and Evolution Research Centre, and Department of Anthropology, Durham University, UK;2. Biology, Chester University, Chester, UK;3. Department of Anthropology, University of Utah, UT, USA |
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| Abstract: | A review of experimental data on the steroid regulation of sexual behavior in the rat suggests that estrogen is involved in the control of both male and female sexual behavior. Female sexual behavior is stimulated by estrogen alone or in combination with progesterone and by aromatizable androgens. In the male, testosterone, androstenediol, and androstenedione were effective in the control of male sexual behavior. Estrogen alone may initiate and restore full masculine copulatory behavior in sexually castrated males. Estrogen may also synergize with nonaromatizable androgens and control behavior. While antiestrogens are ineffective in inhibiting sexual behavior, aromatization blockers (primarily aminoglutethimide) can block sexual response in the presence of aromatizable androgens. |
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