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Enhancement of chrysogenin production in cultures of Penicillium chrysogenum by uronic acid oligosaccharides
Authors:E Asilonu  C Bucke  T Keshavarz
Institution:(1) Fungal Biotechnology Group, Biotechnology Department, University of Westminster, 115 New Cavendish Street, London , W1M 8JS, UK
Abstract:Additions of 50 to 100 mgrg of acid-hydrolysed alginate oligosaccharides ml–1 and enzyme-hydrolysed pectin oligosaccharides to 24- to 48-h cultures of Penicillium chrysogenum, ATCC 9480, led to enhanced production of chrysogenin by over 30 to 40% in shaken flasks and bioreactors. Some of the oligosaccharides also promoted biomass formation but were not used as a carbon source.
Keywords:chrysogenin  elicitors  enhancement  oligosaccharides  Penicillium chrysogenum
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