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Improving expression of recombinant human IGF‐1 using IGF‐1R knockout CHO cell lines
Authors:Sandrine Romand  Thomas Jostock  Mara Fornaro  Joerg Schmidt  Anett Ritter  Burkhard Wilms  Holger Laux
Affiliation:1. Integrated Biologics Profiling, Novartis Pharma, Basel, Switzerland;2. Musculoskeletal Diseases, Novartis Institute for BioMedical Research, Basel, Switzerland;3. Cell and Gene Therapies, Novartis Pharma, Basel, Switzerland;4. +41‐0‐61‐696‐3511+41‐0‐61‐696‐3373
Abstract:
Keywords:CHO  IGF‐1  IGF‐1R  cell line engineering  ZFN  Chinese hamster ovary
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