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A hybrid approach identifies metabolic signatures of high‐producers for chinese hamster ovary clone selection and process optimization |
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| Authors: | Oliver Popp Dirk Müller Katharina Didzus Wolfgang Paul Florian Lipsmeier Florian Kirchner Jens Niklas Klaus Mauch Nicola Beaucamp |
| Affiliation: | 1. +49 8856 60 18420;2. Pharma Research and Early Development, Cell Culture Research, Roche Innovation Center Penzberg, Roche Diagnostics GmbH, D‐82377 Penzberg, Germany;3. Insilico Biotechnology AG, Stuttgart, Germany;4. Pharma Research and Early Development, pRED Informatics, Roche Innovation Center Penzberg, Roche Diagnostics GmbH, Penzberg, Germany |
| Abstract: | |
| Keywords: | CHO Cells clone Selection process Optimization metabolic flux analysis |