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High throughput chromatography strategies for potential use in the formal process characterization of a monoclonal antibody
Authors:Matthew G Petroff  Haiying Bao  John P Welsh  Miranda van Beuningen – de Vaan  Jennifer M Pollard  David J Roush  Sunitha Kandula  Peter Machielsen  Nihal Tugcu  Thomas O Linden
Institution:1. Process Development and Engineering, Merck & Co. Inc., Kenilworth, New Jersey;2. 908‐740‐0774908‐740‐2387;3. Downstream Processing, Merck & Co. Inc., Oss, The Netherlands
Abstract:
Keywords:monoclonal antibody  high throughput process development  process characterization  anion exchange chromatography  cation exchange chromatography
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