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Genome‐scale RNA interference screen identifies antizyme 1 (OAZ1) as a target for improvement of recombinant protein production in mammalian cells
Authors:Su Xiao  Yu Chi Chen  Eugen Buehler  Swati Mandal  Ajeet Mandal  Michael Betenbaugh  Myung Hee Park  Scott Martin  Joseph Shiloach
Affiliation:1. Biotechnology Core Laboratory NIDDK, NIH, Bethesda, Maryland;2. Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland;3. Chemical Genomics Center, National Center for Advancing Translational Sciences, NIH, Rockville, Maryland;4. Molecular and Cellular Biochemistry Section, NIDCR, NIH, Bethesda, Maryland;5. +1‐650‐255‐6724;6. +1‐301‐496‐9719+1‐301‐496‐5911
Abstract:
Keywords:siRNA  HEK 293  OAZ1  luciferase  protein production
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