Bacteriocin (mutacin) production by Streptococcus mutans genome sequence reference strain UA159: elucidation of the antimicrobial repertoire by genetic dissection |
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| Authors: | Hale John D F Ting Yi-Tian Jack Ralph W Tagg John R Heng Nicholas C K |
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| Affiliation: | Department of Microbiology and Immunology, University of Otago, P.O. Box 56, Dunedin, New Zealand. |
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| Abstract: | Streptococcus mutans UA159, the genome sequence reference strain, exhibits nonlantibiotic mutacin activity. In this study, bioinformatic and mutational analyses were employed to demonstrate that the antimicrobial repertoire of strain UA159 includes mutacin IV (specified by the nlm locus) and a newly identified bacteriocin, mutacin V (encoded by SMU.1914c). |
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